Blar i forfatter "Hodge, Allison M."

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    • Appraising the causal relevance of DNA methylation for risk of lung cancer 

      Battram, Thomas; Richmond, Rebecca C.; Baglietto, Laura; Haycock, Philip C.; Perduca, Vittorio; Bojesen, Stig E.; Gaunt, Tom R.; Hemani, Gibran; Guida, Florence; Carreras-Torres, Robert; Hung, Rayjean; Amos, Christopher I.; Freeman, Joshua R.; Sandanger, Torkjel M; Nøst, Therese Haugdahl; Nordestgaard, Børge G.; Teschendorff, Andrew E.; Polidoro, Silvia; Vineis, Paolo; Severi, Gianluca; Hodge, Allison M.; Giles, Graham G; Grankvist, Kjell; Johansson, Mikael B.; Johansson, Mattias; Smith, George Davey; Relton, Caroline L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-24)
      <i>Background</i> - DNA methylation changes in peripheral blood have recently been identified in relation to lung cancer risk. Some of these changes have been suggested to mediate part of the effect of smoking on lung cancer. However, limitations with conventional mediation analyses mean that the causal nature of these methylation changes has yet to be fully elucidated.<p> <p><i>Methods</i> - We ...

    • Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. 

      Magnussen, Christina; Ojeda, Francisco M.; Leong, Darryl P.; Alegre-Diaz, Jesus; Amouyel, Philippe; Aviles-Santa, Larissa; De Bacquer, Dirk; Ballantyne, Christie M.; Bernabé-Ortiz, Antonio; Bobak, Martin; Brenner, Hermann; Carrillo-Larco, Rodrigo M.; De Lemos, James; Dobson, Annette; Dörr, Marcus; Donfrancesco, Chiara; Drygas, Wojciech; Dullaart, Robin P.; Engström, Gunnar; Ferrario, Marco M.; Ferrières, Jean; De Gaetano, Giovanni; Goldbourt, Uri; Gonzalez, Clicerio; Grassi, Guido; Hodge, Allison M.; Hveem, Kristian; Iacoviello, Licia; Ikram, M. Kamran; Irazola, Vilma; Jobe, Modou; Jousilahti, Pekka; Kaleebu, Pontiano; Kavousi, Maryam; Kee, Frank; Khalili, Davood; Koenig, Wolfgang; Kontsevaya, Anna; Kuulasmaa, Kari; Lackner, Karl J.; Leistner, David M.; Lind, Lars; Linneberg, Allan; Lorenz, Thiess; Lyngbakken, Magnus Nakrem; Malekzadeh, Reza; Malyutina, Sofia; Mathiesen, Ellisiv B.; Melander, Olle; Metspalu, Andres; Miranda, J. Jaime; Moitry, Marie; Mugisha, Joseph; Nalini, Mahdi; Nambi, Vijay; Ninomiya, Toshiharu; Oppermann, Karen; D'Orsi, Eleonora; Pająk, Andrzej; Palmieri, Luigi; Panagiotakos, Demosthenes; Perianayagam, Arokiasamy; Peters, Annette; Poustchi, Hossein; Prentice, Andrew M.; Prescott, Eva; Risérus, Ulf; Salomaa, Veikko; Sans, Susana; Sakata, Satoko; Schöttker, Ben; Schutte, Aletta E.; Sepanlou, Sadaf G.; Sharma, Sanjib Kumar; Shaw, Jonathan E.; Simons, Leon A.; Söderberg, Stefan; Tamosiunas, Abdonas; Thorand, Barbara; Tunstall-Pedoe, Hugh; Twerenbold, Raphael; Vanuzzo, Diego; Veronesi, Giovanni; Waibel, Julia; Wannamethee, S. Goya; Watanabe, Masafumi; Wild, Philipp S.; Yao, Yao; Zeng, Yi; Ziegler, Andreas; Blankenberg, Stefan (Journal article; Tidsskriftartikkel; Peer reviewed, 2023)
      BACKGROUND - Five modifiable risk factors are associated with cardiovascular disease and death from any cause. Studies using individual-level data to evaluate the regional and sex-specific prevalence of the risk factors and their effect on these outcomes are lacking.<p> <p>METHODS - We pooled and harmonized individual-level data from 112 cohort studies conducted in 34 countries and 8 geographic ...

    • Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer: A pooled analysis of data from two prospective cohort studies 

      Jayasekara, Harindra; MacInnis, Robert J.; Lujan-Barroso, Leila; Mayen-Chacon, Ana-Lucia; Cross, Amanda J.; Wallner, Bengt; Palli, Domenico; Ricceri, Fulvio; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Kühn, Tilman; Kaaks, Rudolf; Tsilidis, Konstantinos K.; Sánchez, Maria-Jose; Amiano, Pilar; Ardanaz, Eva; Chirlaque López, María Dolores; Merino, Susana; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Sternby, Hanna; Sonestedt, Emily; Bueno-de-Mesquita, Bas; Boeing, Heiner; Travis, Ruth C.; Sandanger, Torkjel M; Trichopoulou, Antonia; Karakatsani, Anna; Peppa, Eleni; Tjønneland, Anne; Yang, Yi; Hodge, Allison M.; Mitchell, Hazel; Haydon, Andrew; Room, R; Hopper, John L.; Weiderpass, Elisabete; Gunter, Marc J.; Riboli, Elio; Giles, Graham G.; Milne, Roger L.; Agudo, Antonio; English, Dallas R.; Ferrari, Pietro (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-07)
      Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long-term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a pooled analysis of data collected at baseline from 491 714 participants in the European Prospective Investigation into Cancer and Nutrition and the Melbourne ...

    • Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: A multi-cohort analysis 

      Fiorito, Giovanni; McCrory, Cathal; Robinson, Oliver; Carmeli, Cristian; Rosales, Carolina Ochoa; Zhang, Yan; Colicino, Elena; Dugué, Pierre-Antoine; Artaud, Fanny; McKay, Gareth J.; Jeong, Ayoung; Mishra, Pashupati P.; Nøst, Therese Haugdahl; Krogh, Vittorio; Panico, Salvatore; Sacerdote, Carlotta; Tumino, Rosario; Palli, Domenico; Matullo, Giuseppe; Guarrera, Simonetta; Gandini, Martina; Bochud, Murielle; Dermitzakis, Emmanouil; Muka, Taulant; Schwartz, Joel; Vokonas, Pantel S.; Just, Allan; Hodge, Allison M.; Giles, Graham G.; Southey, Melissa C.; Hurme, Mikko A.; Young, Ian; McKnight, Amy Jayne; Kunze, Sonja; Waldenberger, Melanie; Peters, Annette; Schwettmann, Lars; Lund, Eiliv; Baccarelli, Andrea; Milne, Roger L.; Kenny, Rose A.; Elbaz, Alexis; Brenner, Hermann; Kee, Frank; Voortman, Trudy; Probst-Hensch, Nicole; Lehtimäki, Terho; Elliot, Paul; Stringhini, Silvia; Vineis, Paolo; Polidoro, Silvia (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-14)
      <p>Differences in health status by socioeconomic position (SEP) tend to be more evident at older ages, suggesting the involvement of a biological mechanism responsive to the accumulation of deleterious exposures across the lifespan. DNA methylation (DNAm) has been proposed as a biomarker of biological aging that conserves memory of endogenous and exogenous stress during life. <p>We examined the ...